CONAN has four input types: Multiple Sequence Alignment file, FASTA sequence, PFAM ID and Uniprot ID.

The input multiple sequence alignment file must be in one of the formats: Selex, Stockholm or Fasta. It is also recommended that the sequence labels follows the Pfam format (i.e. [entry name or accession code]/offsets), otherwise the application will not be able to match UniprotKb annotations to the sequences. A sample can be accessed here

The FASTA sequence input must be pasted in their corresponded field. After submit the sequence, CONAN will perform a HmmerScan and you must select what domain is going to be analyzed.

Restrictions:

• 50mb maximum input file.
• Maximum number of sequences: 4.000 sequences if you include marginal conservation, otherwise 15.000.

For larger inputs please download our desktop scripts.